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Nitric oxide generation, tachyphylaxis and cross-tachyphylaxis from nitrovasodilators in vivo

✍ Scribed by Per Agvald; L.Christofer Adding; Lars E Gustafsson; Magnus G Persson

Book ID: 114017644
Publisher: Elsevier Science
Year: 1999
Tongue: English
Weight: 256 KB
Volume: 385
Category: Article
ISSN: 0014-2999
DOI: 10.1016/s0014-2999(99)00720-7

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## Abstract The authors have shown direct, real‐time, __in vivo__ measurement of nitric oxide (NO) in mice by using the water soluble metal chelator complex, __N__‐methyl‐D‐glucamine dithiocarbamate (MGD), and Fe(II) as monitored by EPR at L‐band. The three‐line EPR spectrum from the product [(MGD)