## Abstract Inflammatory‐activated glia are seen in numerous central nervous system (CNS) pathologies and can kill nearby neurons through the release of cytotoxic mediators. Glia, when activated, can express the inducible isoform of nitric oxide synthase (iNOS) producing high levels of nitric oxide
✦ LIBER ✦
Nitric oxide from neuronal nitric oxide synthase sensitises neurons to hypoxia-induced death via competitive inhibition of cytochrome oxidase
✍ Scribed by Aiste Jekabsone; Jonas J. Neher; Vilmante Borutaite; Guy C. Brown
- Book ID
- 111180321
- Publisher
- John Wiley and Sons
- Year
- 2007
- Tongue
- English
- Weight
- 344 KB
- Volume
- 0
- Category
- Article
- ISSN
- 0022-3042
No coin nor oath required. For personal study only.
📜 SIMILAR VOLUMES
Nitric oxide from inflammatory-activated
✍
Palwinder Mander; Vilma Borutaite; Salvador Moncada; Guy C. Brown
📂
Article
📅
2004
🏛
John Wiley and Sons
🌐
English
⚖ 475 KB
Total sleep deprivation inhibits the neu
✍
Hung-Ming Chang; Un-In Wu; Tzer-Bin Lin; Chyn-Tair Lan; Wei-Ching Chien; Wei-Lin
📂
Article
📅
2006
🏛
John Wiley and Sons
🌐
English
⚖ 314 KB
Loss of dopaminergic neurons by the indu
✍
Tatsusada Okuno; Yuji Nakatsuji; Atsushi Kumanogoh; Masayuki Moriya; Hiroshi Ich
📂
Article
📅
2005
🏛
John Wiley and Sons
🌐
English
⚖ 1018 KB
## Abstract A glial reaction associated with up‐regulation of inflammatory molecules has been suggested to play an important role in dopaminergic neuron loss in Parkinson's disease (PD). Among inflammatory molecules, inducible nitric oxide synthase (iNOS) and cyclooxygenase‐2 (COX‐2) have been focu