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Nitric oxide donor increases the efficiency of cytostatic therapy and retards the development of drug resistance

✍ Scribed by N.P Konovalova; S.A Goncharova; L.M Volkova; T.A Rajewskaya; L.T Eremenko; A.M Korolev


Book ID
117730884
Publisher
Elsevier Science
Year
2003
Tongue
English
Weight
293 KB
Volume
8
Category
Article
ISSN
1089-8603

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Nitric Oxide (NO) is a pleitropic, ubiquitous modulator of cellular functions. Aryl nitrite and glyceryl trinitrate, representative intravasadilators, were introduced as therapeutic agents more than a century ago for relief from acute attacks of angina. The vasodilator action is mediated by the rele