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Nitric Oxide Decreases Oxidant-Mediated Hepatocyte Injury

โœ Scribed by Paul C. Kuo; Adam Slivka


Book ID
115634587
Publisher
Elsevier Science
Year
1994
Tongue
English
Weight
474 KB
Volume
56
Category
Article
ISSN
0022-4804

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Nitric oxide protects rat hepatocytes ag
โœ Jae-Sung Kim; Shigetoshi Ohshima; Peter Pediaditakis; John J. Lemasters ๐Ÿ“‚ Article ๐Ÿ“… 2004 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 340 KB

We investigated the effects of nitric oxide (NO) on hepatocellular killing after simulated ischemia/reperfusion and characterized signaling factors triggering cytoprotection by NO. Cultured rat hepatocytes were incubated in anoxic Krebs-Ringer-HEPES buffer at pH 6.2 for 4 hours and reoxygenated at p