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Nitric oxide and superoxide radical are involved in both initiation and development of adjuvant arthritis in rats

✍ Scribed by Yoshihiko Oyanagui

Book ID
118346988
Publisher
Elsevier Science
Year
1994
Tongue
English
Weight
278 KB
Volume
54
Category
Article
ISSN
0024-3205

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Endothelial dysfunction in rat adjuvant-induced arthritis: Vascular superoxide production by NAD(P)H oxidase and uncoupled endothelial nitric oxide synthase
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## Abstract ## Objective To investigate endothelial function and levels of vascular oxidative stress in rat adjuvant‐induced arthritis (AIA), in view of mounting evidence for an association between rheumatoid arthritis (RA) and accelerated vascular disease. ## Methods Thoracic aortic rings were