Nitric oxide and portal hypertension: Interface of vasoreactivity and angiogenesis
β Scribed by Daniel A. Langer; Vijay H. Shah
- Book ID
- 116650928
- Publisher
- Elsevier Science
- Year
- 2006
- Tongue
- English
- Weight
- 304 KB
- Volume
- 44
- Category
- Article
- ISSN
- 0168-8278
No coin nor oath required. For personal study only.
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Systemic and especially splanchnic arterial vasodilation accompany chronic portal hypertension. Different soluble mediators causing this vasodilation have been proposed, the strongest evidence being for nitric oxide (NO). No data exist if structural vascular changes may partly account for this vasod
The effects of inhibiting endogenous nitric oxide (NO) synthesis with W-monomethyl-L-arginine (L-NMMA) on the systemic and splanchnic circulation have been investigated in rats with experimental chronic portal hypertension, anaesthetized with ketamine. 2 Portal hypertension was induced by partial p