✦ LIBER ✦
Nitration and hydroxylation of substituted phenols by peroxynitrite. Kinetic feature and an alternative mechanistic view
✍ Scribed by Nobuaki Nonoyama; Kazuhiko Chiba; Kaori Hisatome; Hitomi Suzuki; Futoshi Shintani
- Publisher
- Elsevier Science
- Year
- 1999
- Tongue
- French
- Weight
- 257 KB
- Volume
- 40
- Category
- Article
- ISSN
- 0040-4039
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✦ Synopsis
The reaction of peroxynitrite (ONOO-) with a series ofpara-substituted phenols has been examined in aqueous phosphate buffer and acetonitrile solutions. Major products were the corresponding 2-nitro derivative and the 4-substituted catechol. Kinetic study showed good correlation with Hammett (rp ÷ parameters and reduction potentials, suggesting the possible one-electron transfer process involving the nitrosoniun ion (NO +) as initial electrophile generated from peroxynitrous acid.