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Nitrated polycyclic aromatic hydrocarbons and azaarenes induce cytochrome P4501A in a fish hepatoma cell line

โœ Scribed by K. Fent; D.K.J. Jung


Book ID
117313561
Publisher
Elsevier Science
Year
2000
Tongue
English
Weight
63 KB
Volume
50
Category
Article
ISSN
0141-1136

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## Abstract The polycyclic aromatic hydrocarbons (PAHs) phenanthrene and retene (7โ€isopropylโ€1โ€methyl phenanthrene) are lethal to rainbow trout __(Oncorhynchus mykiss)__ larvae during chronic exposures. Phenanthrene is a lowโ€toxicity, nonโ€cytochrome P4501A (CYP1A)โ€”inducing compound that accumulates