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Nitrated Hsp90 Decreases Mitochondrial Membrane Potential and Oxygen Consumption

✍ Scribed by Maria Clara Franco; Karina Ricart; Sarah Gitto; Mike Janes; Landon Wilson; Stephen Barnes; Aimee Landar; Alvaro G. Estevez

Book ID
113632160
Publisher
Elsevier Science
Year
2011
Tongue
English
Weight
54 KB
Volume
51
Category
Article
ISSN
0891-5849

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## Abstract Increasing evidence indicates that mitochondrial alterations contribute to the neuronal death in Alzheimer's disease (AD). Presenilin 1 (PS1) and Presenilin 2 (PS2) mutations have been shown to sensitize cells to apoptosis by mechanisms suggested to involve impaired mitochondrial functi