## Abstract To evaluate the role of soluble mediators released after interaction of leukocytes with biomaterials on cells of the implant microenvironment, the surface expression of adhesion molecules (CD11b, CD62L, CD66b, ICAM‐1) on freshly isolated whole blood leukocytes (WBL) was analyzed by flow
NiTi shape memory alloys coated with calcium phosphate by plasma-spraying. Chemical and biological properties
✍ Scribed by O. Prymak; D. Bogdansk; S.A. Esenwein; M. Köller; M. Epple
- Publisher
- John Wiley and Sons
- Year
- 2004
- Tongue
- English
- Weight
- 563 KB
- Volume
- 35
- Category
- Article
- ISSN
- 0933-5137
No coin nor oath required. For personal study only.
✦ Synopsis
Abstract
Plates of superelastic nickel‐titanium shape memory alloy (NiTi) were coated with calcium phosphate (hydroxyapatite) by high‐temperature plasma‐spraying. The porous layer of about 100 μm thickness showed a good adhesion to the metallic substrate that withstood bending of the plate but detached upon cutting the plate. The biocompatibility was tested by cultivation of blood cells (whole blood and isolated granulocytes [a subpopulation of blood leukocytes]). As substrates, pure NiTi, plasma‐spray‐coated NiTi and calcium phosphate‐coated NiTi prepared by a dip‐coating process were used. The adhesion of whole blood cells to all materials was not significantly different. In contrast, isolated granulocytes showed an increased adhesion to both calcium phosphate‐coated NiTi samples. However, compared to non‐coated NiTi or dip‐coated NiTi, the number of dead granulocytes adherent to plasma‐sprayed surfaces was significantly increased for isolated granulocytes (p<0.01).
📜 SIMILAR VOLUMES