Nitazoxanide or CD3+/CD4+ lymphocytes for recovery from severe Cryptosporidium infection after allogeneic bone marrow transplant?

✍ Scribed by M. Faraci; B. Cappelli; G. Morreale; E. Lanino; C. Moroni; R. Bandettini; M. P. Terranova; D. Di Martino; C. Coccia; E. Castagnola

• Book ID: 110896180
• Publisher: John Wiley and Sons
• Year: 2007
• Tongue: English
• Weight: 675 KB
• Volume: 11
• Category: Article
• ISSN: 1397-3142
• DOI: 10.1111/j.1399-3046.2006.00622.x

✦ Synopsis

Abstract: We describe a case of Cryptosporidium infection occurring in a child after allogeneic SCT for acute non‐lymphoblastic leukemia. This patient presented an intestinal, biliar, and pancreatic Cryptosporidium disease associated with an intestinal aGvHD. The increase in CD3+/CD4+ cells secondary to the reduction of steroid therapy associated with the improvement of aGvHD and the use of antiparasitic treatments (especially nitazoxanide) improved the infection‐related symptoms and led to a complete clearance of the Cryptosporidium.