𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Nimesulide limits kainate-induced oxidative damage in the rat hippocampus

✍ Scribed by Eduardo Candelario-Jalil; Hussam H Ajamieh; Susana Sam; Gregorio Martı́nez; Olga S León Fernández

Book ID
114017824
Publisher
Elsevier Science
Year
2000
Tongue
English
Weight
88 KB
Volume
390
Category
Article
ISSN
0014-2999

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

Effects of nimesulide on kainate-induced
Effects of nimesulide on kainate-induced in vitro oxidative damage in rat brain homogenates
✍ Eduardo Candelario-Jalil; Olga Sonia León 📂 Article 📅 2003 🏛 BioMed Central 🌐 English ⚖ 646 KB

## Background: The cyclooxygenase-2 inhibitor nimesulide is able to reduce kainate-induced oxidative stress in vivo. here we investigate if this effect is mediated by the direct antioxidant properties of nimesulide using a well-characterized in vitro model of kainate toxicity. ## Results: Exposur

Selective vulnerability to kainate-induc
Selective vulnerability to kainate-induced oxidative damage in different rat brain regions
✍ Eduardo Candelario-Jalil; Saied Mohammed Al-Dalain; Rubén Castillo; Gregorio Mar 📂 Article 📅 2001 🏛 John Wiley and Sons 🌐 English ⚖ 97 KB

## Abstract Some markers of oxidative injury were measured in different rat brain areas (hippocampus, cerebral cortex, striatum, hypothalamus, amygdala/piriform cortex and cerebellum) after the systemic administration of an excitotoxic dose of kainic acid (KA, 9 mg kg^−1^ i.p.) at two different sam