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Nigral pathology in older persons without Parkinson disease

✍ Scribed by Kurt A. Jellinger; Johannes Attems


Book ID
115549575
Publisher
John Wiley and Sons
Year
2012
Tongue
English
Weight
63 KB
Volume
72
Category
Article
ISSN
0364-5134

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πŸ“œ SIMILAR VOLUMES


Nigral pathology and parkinsonian signs
✍ Aron S. Buchman; Joshua M. Shulman; Sukriti Nag; Sue E. Leurgans; Steven E. Arno πŸ“‚ Article πŸ“… 2012 πŸ› John Wiley and Sons 🌐 English βš– 958 KB

## Abstract ## Objective: Motor symptoms such as mild parkinsonian signs are common in older persons, but little is known about their underlying neuropathology. We tested the hypothesis that nigral pathology is related to parkinsonism in older persons without Parkinson disease (PD). ## Methods:

Nigral degeneration in parkinson's disea
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Neuronal loss in the substantia nigra of patients with Parkinson's disease (PD) does not occur evenly throughout the nucleus: the ventrolateral part of the substantia nigra degenerates more severely, whereas the medial part is relatively preserved. This pattern of nigral neuronal loss is compatible