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Nicotinic acetylcholine receptor (nAChR) desensitization and its relevance to physiological and behavioral functions

✍ Scribed by M. Shachar; H. Cohen; E. Heldman


Book ID
118593368
Publisher
Elsevier Science
Year
2006
Tongue
English
Weight
103 KB
Volume
16
Category
Article
ISSN
0924-977X

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## Abstract Cembranoids are cyclic diterpenoids found in tobacco and in marine invertebrates. The present study established that tobacco cembranoids inhibit behavioral sensitization to nicotine in rats and block several types of nicotine acetylcholine receptors (AChRs). 1) At the behavioral level,