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Nicotine stereoisomers and cotinine stimulate prostaglandin E2 but inhibit thromboxane B2 and leukotriene E4 synthesis in whole blood

✍ Scribed by Virpi Saareks; István Mucha; Eeva Sievi; Heikki Vapaatalo; Asko Riutta

Book ID
114016396
Publisher
Elsevier Science
Year
1998
Tongue
English
Weight
111 KB
Volume
353
Category
Article
ISSN
0014-2999

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Simultaneous determination of thromboxan
Simultaneous determination of thromboxane B2, prostaglandin E2 and leukotriene B4 in whole blood by liquid chromatography/mass spectrometry
✍ Yoshiya Oda; Nariyasu Mano; Naoki Asakawa 📂 Article 📅 1995 🏛 John Wiley and Sons 🌐 English ⚖ 674 KB

## Abstract Thromboxane B~2~, prostaglandin E~2~ and leukotriene B~4~ were simultaneously extracted from human whole blood without any time‐consuming evaporation or derivatization process, and directly determined by liquid chromatography/ionspray mass spectrometry. In order to obtain high sensitivi