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Nicotine patches in Alzheimer's disease: Pilot study on learning, memory, and safety

✍ Scribed by A.Lynn Wilson; Linda K Langley; Jan Monley; Timothy Bauer; Sue Rottunda; Edward McFalls; Craig Kovera; J.Riley McCarten

Book ID
113226540
Publisher
Elsevier Science
Year
1995
Tongue
English
Weight
741 KB
Volume
51
Category
Article
ISSN
0091-3057

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In the tu'st study to examine direct nicotinic augmentation of central cholinergic functioning in Alzheimer's disease, six patients were studied in an intensive pilot study with three doses (0.125, 0.25, and 0.5 I~g/kg/min) of intravenous nicotine and placebo. Cognitive tests showed a decrease in in