Nicotine-mecamylamine interactions
โ Scribed by Zevin, S
- Book ID
- 111726801
- Publisher
- Nature Publishing Group
- Year
- 2000
- Tongue
- English
- Weight
- 71 KB
- Volume
- 68
- Category
- Article
- ISSN
- 0009-9236
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๐ SIMILAR VOLUMES
Acute administration of mecamylamine, a centrally active nicotinic cholinergic agonist, has been shown to increase amount of smoking as indicated by smoking topography (e.g., puff rate, puff duration), expired carbon monoxide changes, and other inferential measures. In the present study, subjects sh
I n rats, the effects of an intracerebroventricular (ICV) nicotinic agonist nicotine (NIC), the nicotinic antagonist mecamylamine (MEC), and combinations of NIC + MEC were assessed in a radial-arm maze (RAM). In experiment 1, exploratory behavior was assessed in untrained rats (N = 13). The rats rec