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Nicotine-induced vascular endothelial growth factor release via the EGFR-ERK pathway in rat vascular smooth muscle cells

✍ Scribed by Yasunari Kanda; Yasuhiro Watanabe

Book ID
116718975
Publisher
Elsevier Science
Year
2007
Tongue
English
Weight
362 KB
Volume
80
Category
Article
ISSN
0024-3205

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## Abstract Sphingosine 1‐phosphate (S1P) has been shown to regulate expression of several genes in vascular smooth muscle cells (VSMCs) and contributes to arteriosclerosis. However, the mechanisms regulating epidermal growth factor receptor (EGFR) expression by S1P in aortic VSMCs remain unclear.