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Nicotine antagonists: phosphoinositide turnover and receptor binding to determine muscarinic properties

✍ Scribed by Srabani Banerjee; Leo G. Abood

Book ID
115781098
Publisher
Elsevier Science
Year
1989
Tongue
English
Weight
395 KB
Volume
38
Category
Article
ISSN
0006-2952

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## Abstract The binding of one irreversible and two reversible radioactive antagonists to muscarinic receptors in synaptosome preparations of rat cerebral cortex has been studied. The ligands all bind to the same receptor pool and directly and competitively yield self‐consistent binding constants c