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Nicotinamide stimulates repair of DNA damage in human lymphocytes

โœ Scribed by Nathan A. Berger; Georgina W. Sikorski


Book ID
118314594
Publisher
Elsevier Science
Year
1980
Tongue
English
Weight
370 KB
Volume
95
Category
Article
ISSN
0006-291X

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## Abstract The effect of simulated microgravity on DNA damage and apoptosis is still controversial. The objective of this study was to test whether simulated microgravity conditions affect the expression of genes for DNA repair and apoptosis. To achieve this objective, human lymphocyte cells were

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## Abstract The effect of nicotinamide on unscheduled DNA synthesis was studied in resting human lymphocytes. In cells treated with UV irradiation or with MNNG, nicotinamide caused a twoโ€fold stimulation of unscheduled DNA synthesis and retarded the rate of NAD^+^ lowering caused by these treatment