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Nicotinamide inhibits hepatic fibrosis by suppressing DNA synthesis and enhancing apoptosis of hepatic stellate cells

✍ Scribed by Jing Jin; Kyong Bun Lee; Soo Young Park; Ja-June Jang

Publisher
Springer
Year
2011
Tongue
English
Weight
704 KB
Volume
458
Category
Article
ISSN
1432-2307

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## Abstract Magnolol, a hydroxylated biphenyl compound isolated from the Chinese herb Hou p'u of __Magnolia officinalis__, has been reported to have anti‐cancer activity. In the present study, magnolol at very low concentrations of 3–10 ΞΌM inhibited DNA synthesis and decreased cell number in cultur