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Nicorandil-induced Neural Protection might Contribute to the Attenuation of Myocardial Ischemia-Reperfusion Injury

โœ Scribed by Mitsuo Sobajima; Takayuki Suzuki; Akira Matsuki; Norio Igarasi; Nozomu Fujii; Takasi Nozawa; Hirosi Inoue


Book ID
116338079
Publisher
Elsevier Science
Year
2007
Tongue
English
Weight
44 KB
Volume
13
Category
Article
ISSN
1532-8414

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## Abstract Myocardial injury due to ischemiaโ€reperfusion (Iโ€R) damage remains a major clinical challenge. Its pathogenesis is complex including endothelial dysfunction and heightened oxidative stress although the key driving mechanism remains uncertain. In this study we tested the hypothesis that