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Nickel(0)-catalyzed [2 + 2 + 2] cycloaddition of diynes and 3,4-pyridynes: novel synthesis of isoquinoline derivatives

✍ Scribed by Iwayama, Toshihiko; Sato, Yoshihiro


Book ID
121274930
Publisher
Royal Society of Chemistry
Year
2009
Tongue
English
Weight
578 KB
Volume
35
Category
Article
ISSN
1359-7345

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Nickel-Catalyzed [2+2+2] Cycloaddition o
✍ Ryan M. Stolley; Michael T. Maczka; Janis Louie πŸ“‚ Article πŸ“… 2011 πŸ› John Wiley and Sons 🌐 English βš– 463 KB πŸ‘ 1 views

## Abstract A variety of bicyclic __N__,__N__‐disubstituted 2‐aminopyridines have been prepared from diynes and cyanamides by nickel‐catalyzed [2+2+2] cycloaddition reactions. The reactions proceeded at room temperature with low catalyst loading to afford 2‐aminopyridines in good to excellent yield