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Nickel superoxide dismutase: structural and functional roles of Cys2 and Cys6

โœ Scribed by Kelly C. Ryan; Olivia E. Johnson; Diane E. Cabelli; Thomas C. Brunold; Michael J. Maroney


Publisher
John Wiley and Sons
Year
2010
Tongue
English
Weight
615 KB
Volume
15
Category
Article
ISSN
1432-1327

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## Abstract Tubulin is the target for some very powerful antiโ€mitotic and antiโ€tumor drugs. The ฮฒIII tubulin isotype is found in very few normal tissues, but is often found in tumors, where it has been implicated in resistance to antiโ€tumor drugs. The ฮฒIII isotype occurs in fish, amphibians, birds