Nickel chloride inhibits the DNA repair of UV-treated but not methyl methanesulfonate-treated chinese hamster ovary cells
β Scribed by S. F. Lee-Chen; M. C. Wang; C. T. Yu; D. R. Wu; K. Y. Jan
- Book ID
- 112894612
- Publisher
- Humana Press Inc
- Year
- 1993
- Tongue
- English
- Weight
- 610 KB
- Volume
- 37
- Category
- Article
- ISSN
- 0163-4984
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## Abstract Tumor suppressor p53 is an essential regulator in mammalian cellular responses to DNA damage including cell cycle arrest and apoptosis. Our study with Chinese hamster ovary CHOβK1 cells indicates that when p53 expression and its transactivation capacity was inhibited by siRNA, UVCβinduc