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Nickel-Catalyzed Cross-Coupling of Non-activated and Functionalized Alkyl Halides with Alkyl Grignard Reagents

✍ Scribed by Oleg Vechorkin; Xile Hu


Publisher
John Wiley and Sons
Year
2009
Tongue
English
Weight
300 KB
Volume
121
Category
Article
ISSN
0044-8249

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Nickel-and palladium-catalyzed cross-coupling reactions of organic halides with organometallic reagents is one of the most versatile carbonΒ±carbon bond-forming reactions in organic synthesis. [1] In most cases, aryl and vinyl halides are employed as organic halides, yielding sp 2 Β±sp, sp 2 Β±sp 2 , a