NHC-initiated cascade, metal-free synthesis of quinoxaline derivatives under solvent-free conditions
✍ Scribed by Lijiu Gao, Rui Liu, Chenxia Yu, Changsheng Yao…
- Book ID
- 120765996
- Publisher
- Springer Netherlands
- Year
- 2013
- Tongue
- English
- Weight
- 269 KB
- Volume
- 40
- Category
- Article
- ISSN
- 0922-6168
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## Abstract The sequence allows to construct the required indoles from simple precursors, i.e.
## Abstract An efficient and facile synthesis of quinoxaline derivatives in excellent isolated yields by the condensation of 1,2‐diamines and 1,2‐diketones on grinding under solvent‐free conditions at ambient temperature has been developed. The important features of this method are that it is reaso
## Abstract Best results are obtained in the presence of basic alumina; neutral or acidic alumina and silica give slightly lower yields.