✦ LIBER ✦
NH2-terminal sequence of the α andβchains of human DC-1 antigen isolated from the JY cell line. Homology with murine I-A molecules
✍ Scribed by M. Rosa Bono; Jack L. Strominger
- Publisher
- Springer-Verlag
- Year
- 1983
- Tongue
- English
- Weight
- 379 KB
- Volume
- 18
- Category
- Article
- ISSN
- 0093-7711
No coin nor oath required. For personal study only.
✦ Synopsis
The DC-1 antigen has been isolated from the JY cell line (DR4, w6). The amino terminal sequences of its e and/3 chains are both reported and are homologous to the murine I-A antigens. The JY and previously reported LB DC-1 e chain sequences appear to be variants of the DC e chains reported by other authors. The JY DC-1 /~ chain sequence appears to be identical with that deduced from a/~ chain cDNA clone and thus identifies this clone. The JY and LB DC-1 /%chains are clearly different since the latter has a blocked amino terminus.