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NG2/CSPG4 regulates aggrecanase and MMP expression in human chondrocytes

✍ Scribed by N.S. Jamil; A. Azfer; H.E. Sarah; D.M. Salter

Book ID
113734019
Publisher
Elsevier Science
Year
2012
Tongue
English
Weight
46 KB
Volume
20
Category
Article
ISSN
1063-4584

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## Abstract Limited information is available on the expression and role of matrix metalloproteinase (MMP)‐12 in chondrocytes. We characterized the expression mechanism of MMP‐12 and possible function in chondrocytes. Interleukin (IL)‐1Ξ² induced the expression and activation of MMP‐12 in primary cul