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NFκB Silencing Induces Chromatin Acetylation and Ablates Resistance to Cisplatin in Head and Neck Cancer

✍ Scribed by ABRAHAO, ALINE CORREA; ALMEIDA, LUCIANA O.; ROSSELLI-MURAI, LUCIANA K.; GIUDICE, FERNANDA S.; LEOPOLDINO, ANDREIA M.; SQUARIZE, CRISTIANE H.; CASTILHO, ROGERIO M.

Book ID
122209428
Publisher
Elsevier
Year
2014
Tongue
English
Weight
54 KB
Volume
117
Category
Article
ISSN
2212-4403

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## Abstract Molecular mechanisms responsible for tumor resistance to apoptosis often involve the Fas/FasL pathway. While squamous cell carcinomas of the head and neck (SCCHN) express both Fas and FasL, their resistance to self‐induced apoptosis or apoptosis mediated by Fas agonistic antibody (CH‐11