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Nfil3 is a Regulator of IL-12 P40 in Macrophages and Mucosal Immunity

โœ Scribed by Taku Kobayashi; Katsuyoshi Matsuoka; Shehzad Z. Sheikh; Nobuhiko Kamada; Tadakazu Hisamatsu; Jonathan J. Hansen; Kevin R. Doty; Scott D. Pope; Stephen T. Smale; Toshifumi Hibi; Paul B. Rothman; Masaki Kashiwada; Scott E. Plevy


Book ID
119432291
Publisher
Elsevier Science
Year
2011
Tongue
English
Weight
413 KB
Volume
140
Category
Article
ISSN
0016-5085

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PKCฮด regulates IL-12p40/p70 production b
โœ Reto Guler; Mona Afshar; Berenice Arendse; Suraj P. Parihar; Melanie Revaz-Breto ๐Ÿ“‚ Article ๐Ÿ“… 2011 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 397 KB

The protein kinase C (PKC) family is involved in the regulation of many intracellular signalling pathways. Here, we report that the PKCd isoform regulates IL-12p40/p70 production in macrophages and DC and that PKCd deficiency in mice transforms the 129/Sv healer to a non-healer strain during cutaneo