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NF-κB–dependent increase in intrarenal angiotensin II induced by proteinuria

✍ Scribed by TAKASE, OSAMU; MARUMO, TAKESHI; IMAI, NAOHIKO; HIRAHASHI, JUNICHI; TAKAYANAGI, ATSUSHI; HISHIKAWA, KEIICHI; HAYASHI, MATSUHIKO; SHIMIZU, NOBUYOSHI; FUJITA, TOSHIRO; SARUTA, TAKAO


Book ID
109067228
Publisher
Nature Publishing Group
Year
2005
Tongue
English
Weight
508 KB
Volume
68
Category
Article
ISSN
0085-2538

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## Abstract Angiotensin‐II (AII), the dominant effector of the renin–angiotensin system, is involved in the pathogenesis of cardiovascular diseases, such as atherosclerosis. Upregulation of the adhesion molecules VCAM‐1, ICAM‐1, and E‐selectin in endothelial cells by inflammatory cytokines through