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NF-κB p65 repression by the sesquiterpene lactone, Helenalin, contributes to the induction of autophagy cell death

✍ Scribed by Chuan Bian Lim, Pan You Fu, Nung Ky, Hong Shuang Zhu, XiaoLing Feng, Jinming Li, Kandhadayar Gopalan Srinivasan, Mohamed Sabry Hamza, Yan Zhao


Book ID
119899540
Publisher
BioMed Central
Year
2012
Tongue
English
Weight
687 KB
Volume
12
Category
Article
ISSN
1472-6882

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## Abstract The transcription factor nuclear factor‐κB (NF‐κB) has been shown to be constitutively activated in various human malignancies, including leukemia, lymphoma and a number of solid tumors. NF‐κB regulates the transcriptional of genes important for tumor invasion, metastasis and chemoresis