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NF-κB links oestrogen receptor signalling and EMT

✍ Scribed by Radisky, Derek C.; Bissell, Mina J.


Book ID
109911529
Publisher
Nature Publishing Group
Year
2007
Tongue
English
Weight
185 KB
Volume
9
Category
Article
ISSN
1465-7392

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## Abstract Binding of tumor necrosis factor‐α (TNF‐α) to its receptor activates IKK complex, which leads to inducement of NF‐κB activity. Here we report that activation of Mpl ligand is also linked to IKK and NF‐κB activity. Mpl ligand, also known as thrombopoietin (TPO) or megakaryocyte growth an