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NF-κB in Th2 cells : delayed and long-lasting induction through the TCR complex

✍ Scribed by Beatriz Dorado; Pilar Portolés; Sara Ballester


Book ID
101315967
Publisher
John Wiley and Sons
Year
1998
Tongue
English
Weight
173 KB
Volume
28
Category
Article
ISSN
0014-2980

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## Abstract NF‐κB1‐dependent signaling directs the development of CD4^+^ Th2 cells during allergic airway inflammation and protective responses to helminth infection. Here, we show that IL‐4 and IL‐13 production is NF‐κB1‐dependent in mouse OVA‐specific CD4^+^ (OTII) T cells responding to alum‐prec