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NF-κB-Associated MnSOD induction protects against β-amyloid-induced neuronal apoptosis

✍ Scribed by Pradoldej Sompol; Yong Xu; Wanida Ittarat; Chotiros Daosukho; Daret St. Clair


Book ID
111639946
Publisher
Humana Press Inc
Year
2006
Tongue
English
Weight
313 KB
Volume
29
Category
Article
ISSN
0895-8696

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Recent research has focused on soluble oligomeric assemblies of beta-amyloid peptides (Abeta) as the proximate cause of neuroinflammation, synaptic loss, and the eventual dementia associated with Alzheimer's disease (AD). In this study, tripchlorolide (T4), an extract of Tripterygium wilfordii Hook.