NF-κB and cancer: Mechanisms and targets
✍
Michael Karin
📂
Article
📅
2006
🏛
John Wiley and Sons
🌐
English
⚖ 120 KB
## Abstract In addition to being a central coordinator of immune responses, NF‐κB signaling also plays a critical role in cancer development and progression and it may determine the response to therapy. NF‐κB activation was shown to provide a critical mechanistic link between inflammation and cance