CTLA4 ligation attenuates AP-1, NFAT and
✍
J. Henry Fraser; Mercedes Rincón; Kathy D. McCoy; Graham Le Gros
📂
Article
📅
1999
🏛
John Wiley and Sons
🌐
English
⚖ 121 KB
CTLA4 is currently viewed as a late-appearing T cell surface receptor which is able to inhibit the proliferation of activated T cells. We sought to identify how CTLA4 ligation exerts these anti-proliferative effects by studying its influence on the activities of the relevant nuclear transcription fa