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NF-κB activation but not PI3K/Akt is required for dexamethasone dependent protection against TNF-α cytotoxicity in L929 cells

✍ Scribed by Criselda Mendoza-Milla; Catalina Machuca Rodríguez; Emilio Córdova Alarcón; Adriana Estrada Bernal; E. Mayra Toledo-Cuevas; Eduardo Martínez Martínez; Alejandro Zentella Dehesa


Book ID
116465721
Publisher
Elsevier Science
Year
2005
Tongue
English
Weight
310 KB
Volume
579
Category
Article
ISSN
0014-5793

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## Abstract In response to inflammation stimuli, tumor necrosis factor‐α (TNF‐α) induces expression of cell adhesion molecules (CAMs) in endothelial cells (ECs). Studies have suggested that the nuclear factor‐κB (NF‐κB) and the p38 MAP kinase (p38) signaling pathways play central roles in this proc