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Next-generation sequencing for rare genetic disorders

✍ Scribed by Mustafa Tekin


Book ID
108105447
Publisher
Elsevier Science
Year
2011
Tongue
English
Weight
83 KB
Volume
22
Category
Article
ISSN
0958-1669

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## Abstract Next Generation Sequencing represents a powerful tool for detecting genetic variation associated with human disease. Because of the high cost of this technology, it is critical that we develop efficient study designs that consider the trade‐off between the number of subjects (__n__) and