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Next-generation sequencing approaches for genetic mapping of complex diseases

✍ Scribed by Ferran Casals; Youssef Idaghdour; Julie Hussin; Philip Awadalla


Book ID
113730945
Publisher
Elsevier Science
Year
2012
Tongue
English
Weight
944 KB
Volume
248
Category
Article
ISSN
0165-5728

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## Abstract Over the past several years, genome‐wide association studies (GWAS) have succeeded in identifying hundreds of genetic markers associated with common diseases. However, most of these markers confer relatively small increments of risk and explain only a small proportion of familial cluste