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Next-generation DNA sequencing techniques

✍ Scribed by Wilhelm J. Ansorge

Publisher: Elsevier
Year: 2009
Tongue: English
Weight: 372 KB
Volume: 25
Category: Article
ISSN: 1871-6784
DOI: 10.1016/j.nbt.2008.12.009

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## Abstract Next Generation Sequencing represents a powerful tool for detecting genetic variation associated with human disease. Because of the high cost of this technology, it is critical that we develop efficient study designs that consider the trade‐off between the number of subjects (__n__) and