Unexpected allelic heterogeneity and spe
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Emilie Lalonde; Steffen Albrecht; Kevin C.H. Ha; Karine Jacob; Nathalie Bolduc;
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Article
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2010
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John Wiley and Sons
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English
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Protein coding genes constitute approximately 1% of the human genome but harbor 85% of the mutations with large effects on disease-related traits. Therefore, efficient strategies for selectively sequencing complete coding regions (i.e., "whole exome") have the potential to contribute our understandi