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New X-linked syndrome with severe mental retardation, severely impaired vision, severe hearing defect, epileptic seizures, spasticity, restricted joint mobility, and early death

✍ Scribed by Gustavson, Karl-Henrik ;Annerén, Göran ;Malmgren, Helena ;Dahl, Niklas ;Ljunggren, Carl-Gustaf ;Bäckman, Hans


Book ID
102703047
Publisher
John Wiley and Sons
Year
1993
Tongue
English
Weight
857 KB
Volume
45
Category
Article
ISSN
0148-7299

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✦ Synopsis


Abstract

A family with an X‐linked mental retardation syndrome involving seven children in two generations is reported. The syndrome includes microcephaly, severe mental retardation, optic atrophy with severely impaired vision or blindness, a severe hearing defect, spasticity, epileptic seizures, restricted movement of the large joints, and death in infancy or early childhood.

We conclude that this is a distinct, previously unrecognized X‐linked mental retardation syndrome. © 1993 Wiley‐Liss, Inc.