New water-soluble photo crosslinkable polymers based on modified poly(vinyl alcohol)
✍ Scribed by A. Mühlebach; B. Müller; C. Pharisa; M. Hofmann; B. Seiferling; D. Guerry
- Publisher
- John Wiley and Sons
- Year
- 1997
- Tongue
- English
- Weight
- 235 KB
- Volume
- 35
- Category
- Article
- ISSN
- 0887-624X
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✦ Synopsis
Poly(vinyl alcohol) (PVA) was partially modified by polymer analogous reaction with acrylic and methacrylic acid and with 2-vinyl-4,4-dimethyl-azlactone to obtain water-soluble polymers with pendant (meth)acrylate and acrylamide groups. Aqueous solutions of these polymers were crosslinked by UV-irradiation within seconds to form transparent networks with potential for use in contact lenses. The water content of these hydrogels was studied as a function of polymer molecular weight, the acetate, (meth)acrylate, and methacrylamide contents and irradiation conditions. The hydrogels showed good mechanical properties, even at low crosslinker ( õ5 mol %) and high water contents (60-80%). The formation kinetics and stability of aggregates, investigated by combined GPC/light-scattering measurements of samples annealed and/or stored at different temperatures ( 020 to 100ЊC), give insight into PVA secondary structures.