New Triterpenoid and Ergostane Glycosides from the Leaves of Hydrocotyle umbellata L.

✍ Scribed by Adakarleny Sosa; Carmelo Rosquete; Luis Rojas; Laurent Pouységu; Stéphane Quideau; Thomas Paululat; Anne-Claire Mitaine-Offer; Marie-Aleth Lacaille-Dubois

• Publisher: John Wiley and Sons
• Year: 2011
• Tongue: German
• Weight: 191 KB
• Volume: 94
• Category: Article
• ISSN: 0018-019X
• DOI: 10.1002/hlca.201100109

✦ Synopsis

Abstract

Two new triterpenoid glycosides, together with two new ergostane glycosides, umbellatosides A–D (1–4, resp.), have been isolated from the leaves of Hydrocotyle umbellata L. Their structures were established by 2D‐NMR spectroscopic techniques (^1^H,^1^H‐COSY, TOCSY, NOESY, HSQC, and HMBC) and mass spectrometry as 3__β__,22__β__‐dihydroxy‐3‐O‐[α‐L‐rhamnopyranosyl‐(1→2)‐β‐D‐glucuronopyranosyl]olean‐12‐en‐28‐oic acid 28‐O‐β‐D‐glucopyranosyl ester (1), 3‐O‐[α‐L‐rhamnopyranosyl‐(1→2)‐β‐D‐glucuronopyranosyl]oleanolic acid 28‐O‐β‐D‐glucopyranosyl ester (2), (3__β__,11__α__,26)‐ergosta‐5,24(28)‐diene‐3,11,26‐triol 3‐O‐(β‐D‐glucopyranosyl)‐11‐O‐(α‐L‐rhamnopyranosyl)‐26‐O‐β‐D‐glucopyranoside (3), and (3__β__,11__α__,21,26)‐ergosta‐5,24(28)‐diene‐3,11,21,26‐tetrol 3‐O‐(β‐D‐glucopyranosyl)‐11‐O‐(α‐L‐rhamnopyranosyl)‐26‐O‐β‐D‐glucopyranoside (4).