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New tricyclic and tetracyclic pyranocoumarins with an unprecedented C-4 substituent. Structure elucidation of tamanolide, tamanolide D and tamanolide P from Calophyllum inophyllum of French Polynesia

✍ Scribed by T. Leu; P. Raharivelomanana; S. Soulet; J.P. Bianchini; G. Herbette; R. Faure


Publisher
John Wiley and Sons
Year
2009
Tongue
English
Weight
107 KB
Volume
47
Category
Article
ISSN
0749-1581

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✦ Synopsis


Abstract

Three new pyranocoumarin derivatives, tamanolide (1), tamanolide D (2) and tamanolide P (3), were isolated from the almond seeds of Calophyllum inophyllum L. (Clusiaceae) grown in French Polynesia. These compounds, having an unprecedented C‐4 __iso__butyl substituent, have been characterized as a new class of pyranocoumarins called tamanolides. Their structures were elucidated on the basis of 1D and 2D NMR techniques (COSY, NOESY, HSQC and HMBC) in association with MS (HR‐ESI‐MS) data analysis. Copyright © 2009 John Wiley & Sons, Ltd.