New trialkylsilyl enol ether chemistry: new regiospecific methodology for the synthesis of α,β-unsaturated cyclic ketones

✍ Scribed by Philip Magnus; Andrew Evans; Jérôme Lacour

• Publisher: Elsevier Science
• Year: 1992
• Tongue: French
• Weight: 221 KB
• Volume: 33
• Category: Article
• ISSN: 0040-4039
• DOI: 10.1016/s0040-4039(00)79564-5

✦ Synopsis

Treatment of TIPS en01 ethers with PhIO/TMSN3 followed by desilylation/elimination with fluoride ion gives good yields of the a,P-unsaturated ketone.