𝔖 Bobbio Scriptorium
✦   LIBER   ✦

New tools to trace populations of inflammatory cells in the CNS

✍ Scribed by Alexander Flügel; Monika Bradl


Publisher
John Wiley and Sons
Year
2001
Tongue
English
Weight
859 KB
Volume
36
Category
Article
ISSN
0894-1491

No coin nor oath required. For personal study only.

✦ Synopsis


Abstract

Cells of the central nervous system (CNS) and immune system communicate regularly. There is a constant surveillance of the intact, healthy CNS by activated T‐cells, and massive infiltration of the CNS by immune cells under pathological conditions such as neurodegeneration or neuroinflammation. Labeling CNS‐infiltrating T‐cells is an essential tool to identify the signals and mechanisms, which mediate the interaction between immune cells and cells of the CNS. In this article, we will present an overview describing currently used cellular markers and demonstrate how these markers have contributed to our current knowledge of CNS inflammation and immune surveillance. GLIA 36:125–136, 2001. © 2001 Wiley‐Liss, Inc.


📜 SIMILAR VOLUMES


NOD2 plays an important role in the infl
✍ Vinita S. Chauhan; David G. Sterka Jr.; Samantha R. Furr; Amy B. Young; Ian Marr 📂 Article 📅 2009 🏛 John Wiley and Sons 🌐 English ⚖ 739 KB

## Abstract While glial cells are recognized for their roles in maintaining neuronal function, there is growing appreciation that resident central nervous system (CNS) cells initiate and/or augment inflammation following trauma or infection. We have recently demonstrated that microglia and astrocyt

New tools for the analysis of glial cell
✍ Takeshi Awasaki; Tzumin Lee 📂 Article 📅 2011 🏛 John Wiley and Sons 🌐 English ⚖ 360 KB 👁 1 views

## Abstract Because of its genetic, molecular, and behavioral tractability, __Drosophila__ has emerged as a powerful model system for studying molecular and cellular mechanisms underlying the development and function of nervous systems. The __Drosophila__ nervous system has fewer neurons and exhibi