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New Tools for Breaking Barriers to GPCR Expression in E. coli

✍ Scribed by Anne Robinson


Book ID
116664571
Publisher
Elsevier Science
Year
2011
Tongue
English
Weight
94 KB
Volume
408
Category
Article
ISSN
0022-2836

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## Communicated by Davd Valk Deficiency of cystathionine P-synthase (CBS) causes the most common form of inherited homocystinuria. We developed a simple CBS expression system in E. coli to screen for pathogenic mutations in affected individuals. Portions of patient cDNAs were amplified by PCR and